Most drugs of abuse are addictive. Addiction is a chronic, relapsing disease characterized by compulsive drug seeking and use despite negative consequences and by long-lasting changes in the brain. People who are addicted have strong cravings for the drug, making it difficult to stop using. Most drugs alter a person’s thinking and judgment, which can increase the risk of injury or death from drugged driving or infectious diseases (., HIV/AIDS, hepatitis) from unsafe sexual practices or needle sharing. Drug use during pregnancy can lead to neonatal abstinence syndrome, a condition in which a baby can suffer from dependence and withdrawal symptoms after birth. Pregnancy-related issues are listed in the chart below for drugs where there is enough scientific evidence to connect the drug use to negative effects. However, most drugs could potentially harm an unborn baby.
There is no clear cause of appendicitis. Fecal material is thought to be one possible cause of obstruction of the appendix. Bacteria, viruses , fungi, and parasites can result in infection, leading to the swelling of the tissues of the appendix wall. The various infecting organisms include Yersinia species, adenovirus , cytomegalovirus, actinomycosis, Mycobacteria species, Histoplasma species, Schistosoma species, pinworms , and Strongyloides stercoralis . Swelling of the tissue from inflammatory bowel disease such as Crohn's disease also may cause appendicitis.
Absence of or decrease in body movement; absent, missed, or irregular menstrual periods; stopping of menstrual bleeding; anxiety; nervousness; restlessness; bloated full feeling; bloody or cloudy urine; bloody nose; bruising; burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings; burning, dry or itching eyes; change in taste; chills; clumsiness or unsteadiness; coin-shaped lesions on skin; cold sweats; confusion; constipation; cramps; decreased awareness or responsiveness; degenerative disease of the joint; difficult, burning, or painful urination; difficulty in moving; discharge; excessive tearing of eye; discouragement; dizziness; drowsiness; dry mouth; excess air or gas in stomach or intestines; excessive muscle tone; muscle tension or tightness; muscle stiffness; feeling of constant movement of self or surroundings; feeling sad or empty; feeling of warmth or heat; ; flushing or redness of skin, especially on face and neck; frequent urge to urinate; headache; heavy bleeding; irregular heartbeats; irritability; joint pain; swollen joints; lack of appetite; lip smacking ; uncontrolled chewing movements; loss of hair; loss of interest or pleasure; loss of memory; problems with memory; mimicry of speech or movements; muscle aching or cramping; muscle pains or stiffness; mutism; negativism; normal menstrual bleeding occurring earlier, possibly lasting longer than expected; pain; passing gas; peculiar postures or movements, mannerisms or grimacing; puffing of cheeks; rapid or worm-like movements of tongue; redness, swelling, or soreness of tongue; severe sleepiness; shortness of breath; difficult or labored breathing; small red or purple spots on skin; stuffy nose; runny nose; sneezing; redness, pain, swelling of eye, eyelid, or inner lining of eyelid; seeing, hearing, or feeling things that are not there; sensation of spinning; shaking; shortness of breath; hyperventilation; skin rash; sweating; tightness in chest; tiredness; trouble concentrating; trouble in speaking; slurred speech; trouble sleeping; uncontrolled chewing movements; uncontrolled movements of arms and legs; unusual excitement, restlessness, or irritability; wheezing