As we discussed above, Dianabol carries a strong aromatizing nature, and is a C17-aa anabolic steroid; as such, its side-effects will revolve around these factors. As an aromatizing steroid, this means there can be a testosterone to estrogen conversion, and if estrogen levels go to high it can lead to some complications. When estrogen levels increase, the hormone can attach to the receptors and cause gynecomastia (male-breast enlargement) and it can also promote excess water retention and high blood pressure; Dbol is notorious for promoting high blood pressure. Needless to say, if you already suffer from high blood pressure you should not touch this steroid, but if it's healthy you'll need to ensure it stays this way. For this reason, in-order to combat and avoid these estrogenic side-effects of Dbol, the use of an Aromatase Inhibitor (AI) is often advised. It shouldn't be too hard to see how this can help; after all, an AI inhibits aromatase, but it goes a step further by reducing the body's total estrogen levels. Of course, and this cannot be overstressed, you must keep your doses at a responsible level; most will need at least 20mg per day for any anabolic promotion, with a maximum dosing of 50mg per day. It should be noted; if you've never used this steroid before, you should not start with a high end dose; start low and see how you respond.
Here is my review. After one cycle with Anadrol + Testosterone by Crazy Bulk I've gained a lot of muscle mass. Oxymetholone or Androl as we know it seems to be the strongest oral steroid available. I've notice high anabolic and androgenic effect from it. To be honest, I've also noticed some water retention, but I guess that was because the stack was really powerful and it is actually normal to experience such thing. After finishing the cycle the extra water went out of my body. I've sustained most of the gained muscle mass after the cycle. Next thing is to do a cutting cycle after a month off and I will leave my feedback here again.
Neural injections of Bromodeoxyuridine (BrdU) were applied to males of both groups to test for neurogenesis . Analysis showed that testosterone and dihydrotestosterone regulated adult hippocampal neurogenesis (AHN). Adult hippocampal neurogenesis was regulated through the androgen receptor in the wild-type male rats, but not in the TMF male rats. To further test the role of activated androgen receptors on AHN, flutamide , an antiandrogen drug that competes with testosterone and dihydrotestosterone for androgen receptors , and dihydrotestosterone were administered to normal male rats. Dihydrotestosterone increased the number of BrdU cells, while flutamide inhibited these cells.